Most laundry detergents contain enzymes. Basically, they're digesting the dirt off fabrics! Unfortunately, these enzymes can also irritate your baby's thin, delicate skin. ATTITUDE's Sensitive Skin Natural Baby Laundry Detergent uses fragrance-free, worry-free, hypoallergenic ingredients that are as gentle on synthetic and natural fibers as they are on your little one's skin. To be sure, we got it dermatologist tested and certified by the National Eczema Association! This enzyme-free formula works with both standard and HE washing machines, as well as cold water cycles.